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Backed by science

Collagen is the main structural element of skin, accounting for between 70 and 80 per cent of its dry weight. It provides a support structure that ensures skin elasticity, suppleness and hydration.
 
Collagen fibres, which are constructed within fibroblast cells, are responsible for the maintenance of skin tissues. As we age, collagen synthesis decreases and less new collagen fibres are produced. Collagen in the skin also becomes more cross-linked and fragmented. This results in tougher skin, formation of wrinkles and more dry skin due to less ability to bind water.

Proven benefits

3 clinical studies demonstratef the efficacy of Peptan in delivering anti-aging benefits.
Placebo controlled Clinical studies by leading skin institutes show that daily intake of Peptan significantly  improve skin structure and appearance in just one month.3

Many studies have shown that exogenous collagen peptides may act to stimulate fibroblast cell production and increase fibroblast density1-2. These activities promote younger-looking and suppler skin.
In-vitro and ex-vivo results have demonstrated Peptan’s ability to stimulate collagen and hyaluronic acid production in skin cells.
Clinical studies with Peptan collagen peptides found that the women increased skin hydration by 28 % after eight weeks and suppleness by 19 % after 12 weeks3.

Restructuring skin collagen

A recent clinical study performed by COSderma3 in France also demonstrated the effectiveness of Peptan in restructuring skin by decreasing collagen fragmentation and increasing the overall density of collagen.  After 12 weeks of Peptan F intake, there was a 31% change, compared to the start of the study.3 This restructuring of the skin is key to our understanding of how Peptan F can boost the collagen fiber network, providing clear anti-aging benefits and a more youthful appearance.


1. Ohara et al, 2010. Collagen-derived dipeptide, proline-hydroxyproline, stimulates cell proliferation and hyaluronic acid synthesis in cultured human dermal fibroblasts. J Dermato, 374: 330-338

2. Matsuda, N., et al., 2006, Effects of Ingestion of Collagen Peptide on Collagen fibrils and Glycosaminoglycans in the Dermis, Journal of nutritional science and vitaminology, 52:211-215

3. Asserin, J. et al., 2015. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo-controlled clinical trials. Journal of Cosmetic Dermatology, doi: 10.1111/jocd.12174

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